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LITERATURE REVIEW 1) Cigarette smoking effects on the respiratory epithelium The epithelium coating the upper respiratory tract acts as a first line of defense against invasive agents (pollutants, allergens, microorganisms), and it can cause upper airway symptoms and diseases when in contact with these agents.5 Inhaled cigarette smoke, both passively as well as actively, has been associated with chronic irritation and discomfort on the eyes, nose and oropharynx.6 Since 1964, when a report was published about smoking by the U.S

Conversely, male vapers and users of pod-type devices are more likely to perceive e-cigarettes as less harmful than regular cigarettes, possibly influenced by marketing strategies, device characteristics, and risky behavior of males

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A 2011 systematic review and meta-analysis of 58 studies found that children were significantly more likely to take up smoking if exposed to smoking behaviour within their household